Rationale / Objectives
Project/Program Description & Major Achievements
26 patients were involved in the project. Adherence was monitored remotely through eTectRx’s platform, and the researchers conducted brief patient interviews at the end of the 7-day study period. The participating patients ingested a median of six of their 21 pills, with the majority taken within the first three days.
The 26 patients involved in this study had no previous experience with opioids who were discharged from an emergency department with acute fracture pain were approached to participate in the pilot project. A total of 15 patients (10 refused participation and one was unable to complete the study) were provided with 21, 5mg oxycodone digital pills (standard capsules that contain an embedded wireless ingestible sensor). Chemicals in the stomach activate the sensor, which emits a radio frequency that can be captured by a wearable reader. A corresponding app sends these readings to a cloud-based platform, where the care team can view time-stamped dose adherence data for their patients. While there was variability in ingestion patterns, the findings indicate that self-administration will stop well before the supply runs out.
Brigham and Women’s Health Care – the parent corporation for Brigham and Women’s Hospital, Brigham and Women’s Faulkner Hospital and the Brigham and Women’s Physician Organization – includes 150 outpatient practices with over 1,200 physicians.
- The Opioid Crisis: What is it?
- The Opioid Crisis: Preventing Overdose
- The Opioid Crisis: Harm Reduction Strategies
|Accuracy rate||*a total of 112 ingestion events, compared to 134 ingestions based on pill count|
|Average # of pills ingested||6||out of 21 pills given|
|% of dose ingested within the first 3 days||82%|
|% of patients taking opioids at one week||86%||*represents 6 patients who required operative repair|