Antidepressant Skills at Work: Dealing with Mood Problems in the Workplace is a self-care manual authored by scientist-practitioners with expertise in issues relating to workplace mental health and addiction. The Antidepressant Skills Workbook (ASW) gives an overview of depression, explains how it can be effectively managed according to the best available research, and gives a step-by-step guide to changing patterns that trigger depression. In this self-care guide, we show how to use cognitive and behavioural methods to make important changes in thinking and actions that help one to emerge from depression and make it less likely to recur. These methods can be used in combination with depression treatments, increasing their effectiveness. Note that for most people with serious depression, use of this self-help guide alone will not be sufficient to resolve the depression. People with major depression should obtain treatment with antidepressant medication or Cognitive Behavioural Therapy.