Deprescribing Proton Pump Inhibitors in EMR-enabled Primary Care Settings


This toolkit was created to support the implementation of interventions to reduce long-term prescription of proton pump inhibitors (PPI) where an indication is lacking. It can be used by physicians in community practice or by long-term care organizations to help achieve improvements in patient safety related to over-prescribing. By using the interventions mentioned in this toolkit, the Toronto Western Family Health Team was able to reduce patients prescribed PPIs by 26%. Beyond that, 93% of patients had their PPI prescription reassessed.


  • Achieving physician consensus regarding appropriate indications for longterm PPI use
  • Engaging allied health providers in deprescribing initiative
  • Selecting an approach to capturing patients
  • Deprescribing PPIs among eligible patients
  • Proton Pump Inhibitor (PPI) Deprescribing Algorithm
  • Measuring your performance
  • Sustaining early successes
  • Patient resourcesĀ 
  • References
Contact Person/Organization: 

Choosing Wisely Canada

Type of Tool:

Publication Date: 

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Are there long term side effects of proton pump inhibitors or antacid type medications?